It seems that a moderate-fat diet is more conducive to long-term weight loss than a low-fat one. In a study of 101 people at Brigham and Women's Hospital in Boston, half ate a diet with no more than 20 percent of calories from fat, while the other half ate a 35-percent-fat diet. Of the 44 people who remained on their respective regimens a year later, all had lost about 11 pounds even though only 14 of them were on the low-fat diet.
Six months after that, some on the low-fat diet had regained weight, while the moderate-fat eaters kept off their lost weight and were eating a healthier diet with more fiber and vegetables.